Does inflammation contribute to premenstrual symptoms?

ladies with premenstrual symptoms (PMS) including mood swings, weight gain/bloating, and abdominal cramps/back pain have actually elevated quantities of C-reactive protein (CRP), a biomarker of infection connected with increased risk of heart disease. Developing a link between infection and PMS might have crucial implications for treatment and prevention utilizing anti inflammatory agents and for heart disease danger reduction, based on a write-up in Journal of Women's Health, a publication that is peer-reviewed Mary Ann Liebert, Inc., publishers. The content is available free for download on the Journal of Women's Health website until 16, 2016 july.

Ellen Gold, PhD and coauthors, University of California, Davis, analyzed information gathered on a racially and group that is ethnically diverse of females within the learn of Women's wellness throughout the country (SWAN). In the article "The Association of Inflammation with Premenstrual Symptoms," the researchers report a association that is significant a level of high sensitiveness CRP (hs-CRP) >3 mg/L with four associated with the five mood and real symptoms evaluated.

In the accompanying Editorial entitled "Chronic Inflammation and Premenstrual Syndrome: A Missing Link Found?," Elizabeth Bertone-Johnson, ScD, University of Massachusetts, Amherst, states: "Establishing PMS as an condition that is inflammatory that PMS could be a good sentinel of future chronic disease risk...This intriguing possibility also implies that treatment of premenstrual signs with therapies targeting inflammation could have positive effects on long-lasting chronic illness danger."

"The most of women experience at least some symptoms which are premenstrual. Acknowledging an inflammatory that is underlying for PMS would start the doorway to extra therapy and avoidance options and create a new opportunity for long-lasting danger intervention," claims Susan G. Kornstein, MD, Editor-in-Chief of Journal of Women's wellness, Executive Director associated with the Virginia Commonwealth University Institute for Women's wellness, Richmond, VA, and President regarding the Academy of females's wellness.

Article: The Association that is ="nofollow of with Premenstrual Symptoms, silver Ellen B., Wells Craig, and Rasor Marianne O'Neill, Journal of females's Health, doi:10.1089/jwh.2015.5529, published on the web 2 May 2016.